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Anti-HDL antibody produced in chicken
产品编号: | 3367165 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
MDL number | MFCD00162396 |
NACRES | NA.41 |
Immunogen【免疫原】 | HDL human native protein. |
Application【应用】 | Anti-HDL antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. |
Biochem/physiol Actions【生化/生理作用】 | 11β-hydroxysteroid dehydrogenase type 1 is an NADPH-dependent enzyme highly expressed in metabolic tissues that include liver, adipose tissue and the central nervous system. It may contribute to the loss of muscle strength with age and is a key component of sarcopenia. Inhibition of HDL gene may have some therapeutic potential in sarcopenia. HDL gene variation may affect the physiological cortisol levels and the severity of age-related osteoporosis. It is involved in regenerating active glucocorticoids, that are selectively elevated in adipose tissue in human obesity and metabolic syndrome, both associated with chronic low-grade inflammation. HDL acts as an oxidoreductase to yield active glucocorticoids, cortisol or corticosterone. It is expressed in normal human epidermal keratinocytes (NHEKs) and negatively regulates proliferation of NHEKs. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
biological source【生物来源】 | chicken |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
manufacturer/tradename | Genway 15-288-20088F |
technique(s) | western blot: suitable |
UniProt accession no.【UniProt登记号】 | P28845 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... HSD11B1(3290) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |