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Anti-Hepatocyte Growth Factor Receptor antibody produced in goat
| 产品编号： | 3367253 |
| 规格： | lyophilized powder, affinity isolated antibody |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Hepatocyte Growth Factor Receptor antibody produced in goat
Anti-HGF Receptor
基本信息
| MDL number | MFCD03791598 |
| NACRES | NA.41 |
| General description【一般描述】 | Blockade of receptor-ligand interaction: In a functional ELISA, 0.3-1 μg/mL of this antibody will block 50% of the binding of 5 ng/mL of Recombinant Human HGF to immobilized Recombinant Mouse HGF R/cMET Fc Chimera coated at 1 μg/mL (100 μL/well). At 20 μg/mL, this antibody will block >90% of the binding. |
| Immunogen【免疫原】 | purified recombinant mouse hepatocyte growth factor receptor extracellular domain expressed in insect Sf 21 cells. |
| Biochem/physiol Actions【生化/生理作用】 | Hepatocyte Growth Factor (HGF) is a multifunctional, heparin-binding factor that stimulates the proliferation of liver cells. The cellular effects of HGF are mediated by its receptor, c-Met, that leads to significant activation of ERK, Src/FAK, STAT3 and PI3K signaling. Various functions of the HGF/c-Met signaling include proliferation, cell survival, motility, adhesion and tissue regeneration. Apart from liver, HGF also mediates regeneration of kidney, lung and gastro-intestines. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (pH 7.4) with 5% trehalose. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | goat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | mouse |
| technique(s) | immunohistochemistry: 5-15 μg/mL using using cells and tissue western blot: 0.1-0.2 μg/mL |
| UniProt accession no.【UniProt登记号】 | P16056 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Met(17295) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
