Anti-Histone H1.4 antibody produced in rabbit

NA.41

In mammalian cells, four histone H1 variants (H1.2 to H1.5) are found in all somatic cells, and a fifth (H1.1) is present in thymus, testis and spleen, lymphocytic and neuronal cells. K26/H1.4 is present within the flexible N-terminal domain of H1.4 just before the globular domain. Histone modifications are thought to play an important role in cancer and disease.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Linker histone H1 binds to DNA between nucleosomal core particles and is involved in establishing and maintaining higher order chromatin structures. It is covalently modified. Histone H1 phosphorylation occurs at multiple sites including at Ser²⁷ residue. Histone H1.4 is di-methylated or acetylated at Lys²⁶. enhancer of Zeste 2 (Ezh2).

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

antigen ~35 kDa

human

~1.0 mg/mL

western blot: 1-2 μg/mL using acid-extracted fraction of HL60 cells

P10412

dry ice

−20℃

human ... HIST1H1E(3008)

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Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)