您的位置:首页 > 产品中心 > Anti-hprt1 antibody produced in rabbit
Anti-hprt1 antibody produced in rabbit
![](/image/daily/2022/03/25/133444_275143_proimg_3368404.jpg)
产品编号: | 3368404 |
规格: | Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution |
包装规格: | 100 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-hprt1 antibody produced in rabbit
Anti-HGPRT antibody produced in rabbit
Anti-Hypoxanthine-guanine phosphoribosyltransferase antibody produced in rabbit
Anti-HGPRTase antibody produced in rabbit
基本信息
Human Protein Atlas Number【人类蛋白质图谱编号】 | HPA006360 Human Protein Atlas characterization data |
General description【一般描述】 | HPRT1 (hypoxanthine phosphoribosyltransferase 1) enzyme is an essential part of the purine salvage pathway. The corresponding gene is localized to human chromosome Xq26-27, which is composed of nine exons. The encoded protein is composed of 218 amino acids. |
Immunogen【免疫原】 | Hypoxanthine-guanine phosphoribosyltransferase recombinant protein epitope signature tag (PrEST) |
Application【应用】 | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) |
Biochem/physiol Actions【生化/生理作用】 | HPRT1 (hypoxanthine phosphoribosyltransferase 1) functions in the purine salvage pathway, where it recycles guanine and hypoxanthine into available nucleotides. Degree of enzyme inactivity determines the severity of the related disorder. Incomplete inactivation results in Kelley-Seegmiller syndrome, which is characterized by uric acid nephrolithiasis, hyperuricemia, hyperuricaciduria, and gout arthritis. Severest disorder caused by inactivation of this gene is called Lesch-Nyhan disease (LND). |
Features and Benefits【特点和优势】 | Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section. Every Prestige Antibody is tested in the following ways:
|
Linkage【联系】 | Corresponding Antigen APREST71132. |
Physical form【外形】 | Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide |
Legal Information【法律信息】 | Prestige Antibodies is a registered trademark of sigma-aldrich Co. LLC |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
product line【产品线】 | Prestige Antibodies® Powered by Atlas Antibodies |
form【形式】 | buffered aqueous glycerol solution |
species reactivity | human |
packaging【包装】 | antibody small pack of 25 μL |
enhanced validation【增强验证】 | orthogonal RNAseq Learn more about Antibody Enhanced Validation |
technique(s) | immunoblotting: 0.04-0.4 μg/mL immunofluorescence: 0.25-2 μg/mL immunohistochemistry: 1:200-1:500 |
immunogen sequence【免疫原序列】 | SDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMV |
UniProt accession no.【UniProt登记号】 | P00492 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... HPRT1(3251) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |