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Anti-Interleukin-8 antibody produced in goat
| 产品编号： | 3370129 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 0.1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Interleukin-8 antibody produced in goat
Anti-IL-8
Anti-CXCL8
基本信息
| MDL number | MFCD00212220 |
| NACRES | NA.41 |
| General description【一般描述】 | Interleukin 8 (IL-8) is an 8kD, 72 amino acid residue containing cytokine that belongs to C-X-C chemokine family . The IL-8 gene is mapped to human chromosome 4q13.3. |
| Specificity【特异性】 | The antibody will neutralize the biological activity of recombinant and natural human IL-8, but not recombinant human GROα. |
| Immunogen【免疫原】 | recombinant human IL-8 (CXCL8). |
| Application【应用】 | Anti-Interleukin-8 antibody can be used in immunocytochemistry and immunohistochemistry. Anti-Interleukin-8 antibody can be used for the following :
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| Biochem/physiol Actions【生化/生理作用】 | Interleukin 8 (IL-8) stimulates neutrophils to produce lysosomal enzymes along with myeloperoxidase, α-mannosidase and β-glucuronidase . Goat anti-Interleukin-8 antibody reacts specifically with recombinant and natural human IL-8 but not with recombinant human GROα. Elevated expression of the gene is observed in a number of cancers including chronic spontaneous urticaria and breast cancer, thus serves as a prognostic marker for the same. IL-8 regulates the metastasis and angiogenesis processes during cancer development. IL-8 is responsible for epithelial–mesenchymal transition which plays an important role in providing cancer cells the mobility to invade other neighbouring cells, thereby contributing to metastasis. |
| Physical form【外形】 | Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | goat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | human |
| technique(s) | immunocytochemistry: 5-15 μg/mL immunohistochemistry: 5-15 μg/mL neutralization: suitable western blot: 0.1 μg/mL |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... IL8(3576) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
