Anti-LAMP-2 antibody produced in rabbit

MFCD01864612

NA.41

Lamp2 (lysosome-associated membrane protein gene)is located in the lysosomal lumen and lysosomal membrane. However upon chronic acidosis in the tumour microenvironment, it is found to be present in the plasma membrane.

a 17 amino acid peptide from near the center of human LAMP-2.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Anti-LAMP-2 antibody has been used in immunofluorescence and western blot.

LAMP2 (lysosome-associated membrane protein gene) preserves lysosomal membranes from acid proteolysis. It serves as an acidity biomarker in spheroids and xenografts. It also has some role in maturation of autophagic vacuoles and cell-cell or cell-extracellular matrix adhesion. Reduction of LAMP2 (lysosome-associated membrane protein gene) can increase acidosis-mediated toxicity. Mutation in LAMP2 can cause cardiomyopathy in young patients.

The action of this antibody can be blocked using blocking peptide SBP3627.

Solution in phosphate buffered saline containing 0.02% sodium azide

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human, mouse

immunocytochemistry: suitable
indirect ELISA: suitable
western blot: suitable

P17047

dry ice

−20℃

mouse ... Lamp2(16784)

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12 - Non Combustible Liquids

WGK 2