Anti-MAFF (C-Terminal) antibody produced in rabbit

MFCD08705477

NA.41

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF) is a transcription factor which does not have a transactivation domain but possesses a leucine-zipper.
The MAFF gene is located on the human chromosome at 22q13.1. The encoded protein is a small MAF protein and is expressed in the nucleus.

Anti-MAFF (C-terminal) specifically recognizes MAFF.

synthetic peptide corresponding to amino acids 147-163 of human MAFF (isoform a). The immunizing peptide does not cross-react with other members of the family.

Anti-MAFF (c-terminal) antibody produced in rabbit has been used in:

• western blotting
• chromatin immunoprecipitation (chip)
• co-immunoprecipitation
• immunoprecipitation

The small MAF proteins are associated with many physiological processes including development, differentiation, hematopoiesis and stress response. Interestingly, these proteins regulate the stress response via different mechanisms. The MAFF gene is down-regulated in diabetes mellitus 1 patient. This gene is underexpressed in acute lymphoblastic lymphoma (ALL) patients.
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF) has been shown to interact with other transcription factors and it associates with certain regulatory sequences in the gene encoding the oxytocin receptor.

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

rabbit

200

unconjugated

IgG fraction of antiserum

primary antibodies

polyclonal

buffered aqueous solution

antigen 18 kDa

human

immunoprecipitation (IP): 2-4 μL using A431 cell line
microarray: suitable
western blot: 1:2,000-1:4,000 using whole extracts of the A431 cell line

Q9ULX9

dry ice

−20℃

human ... MAFF(23764)

For continuous use, store at 2-8 ℃ for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

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12 - Non Combustible Liquids

WGK 3

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)