广州伟伯科技有限公司
您的位置:首页 > 产品中心 > Anti-Mcl-1 antibody produced in rabbit
产品搜索:

Anti-Mcl-1 antibody produced in rabbit

产品编号:3375808
规格:IgG fraction of antiserum, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3375808100 μG4610
基本信息
MDL number
MFCD01324498
General description【一般描述】
Induced myeloid leukemia cell differentiation protein Mcl-1(MCL1) belongs to the Bcl-2 family and contains the characteristic Bcl-2 homology (BH) domain. The gene encoding this protein is localized on human chromosome 1q21.
Immunogen【免疫原】
Mcl-1 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy-terminus of human Mcl-1.
Biochem/physiol Actions【生化/生理作用】
Induced myeloid leukemia cell differentiation protein Mcl- 1(MCL1) plays an important role in inhibiting apoptosis and is expressed only during particular stages of cell differentiation and in response to specific signals. It is a viability-promoting protein that interacts with fortilin (an anti-apoptotic protein) and regulates cell viability. Specific differentiation- and apoptosis-inducing stimuli enhance the expression of this protein. MCL1 acts as a chaperone of fortilin by binding and stabilizing it. It also interacts and negatively regulates the proliferating cell nuclear antigen (PCNA).
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Linkage【联系】
The action of this antibody can be blocked using blocking peptide SBP3500291.
Physical form【外形】
Supplied in PBS with 0.02% sodium azide.
产品性质
biological source【生物来源】
rabbit
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
IgG fraction of antiserum
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
rat, mouse, human
technique(s)
immunocytochemistry: suitable
immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_068779
UniProt accession no.【UniProt登记号】
Q07820
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... MCL1(4170)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 2
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.0063