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ANTI-MLCK(N-TERMINAL) antibody produced in rabbit
| 产品编号： | 3376795 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 400 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
ANTI-MLCK(N-TERMINAL) antibody produced in rabbit
Myosin light chain kinase
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Myosin light chain kinase (MLCK) is a serine/threonine kinase and the gene encoding it is localized on human chromosome 3q21.1. |
| Biochem/physiol Actions【生化/生理作用】 | Myosin light chain kinase (MLCK) is activated by the binding of Ca2+/calmodulin. It has a role in smooth muscle contraction. The kinase phosphorylates the regulatory light chain of smooth muscle myosin. This stimulates ATPase activity of the myosin heads and leads to the myosin power stroke, which is crucial for muscle contraction. MLCK also assists the interaction of myosin with actin. Loss of function of the protein has been linked to megacystis microcolon intestinal hypoperistalsis syndrome. |
| Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 210715 Da |
| species reactivity | human, mouse |
| technique(s) | immunohistochemistry: 1:50-1:100 western blot: 1:1000 |
| NCBI accession no.【NCBI登记号】 | NP_444253.3 |
| UniProt accession no.【UniProt登记号】 | Q15746 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MYLK(4638) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
