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(11bS)-N,N-二甲基-8,9,10,11,12,13,14,15-八氢二萘并[2,1-d:1′,2′-f][1,3,2]二噁磷杂庚英-4-胺

(11bS)-N,N-dimethyl-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine
产品编号:3377144
CAS NO:389130-06-7
包装规格:100 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
3377144100 MG1300
产品别名

389130-06-7

(11bS)-N,N-二甲基-8,9,10,11,12,13,14,15-八氢二萘并[2,1-d:1′,2′-f][1,3,2]二噁磷杂庚英-4-胺

(11bS)-N,N-dimethyl-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine

MonoPhos Ligand

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C22H26NO2P
Molecular weight
367.42
MDL number
MFCD04117692
PubChem Substance ID【PubChem化学物质编号】
329760980
NACRES
NA.22
Application【应用】
(11bS)-N,N-dimethyl-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine is a monodentate phosphoramidite (MonoPhos) chiral ligand that can be used:
  • In the Cu-catalyzed synthesis of chiral 3-(arylbut-1-yn-1-yl)silane derivatives by reacting N-tosylhydrazones with silyl-substituted alkynes via asymmetric insertion.
  • In the Rh-catalyzed asymmetric hydrogenation of R-isopropylcinnamic acid derivative, a key intermediate of renin inhibitor aliskiren.
  • In the Rh-catalyzed conjugate addition of arylboronic acids to lactones, enones, and nitroalkenes.


DSM MonoPhos Family of Highly Efficient Privileged Ligands
Legal Information【法律信息】
经 DSM 授权销售,仅供研究之用。
产品性质
optical activity【旋光性】
[α]22/D 282.0°, c = 1 in chloroform
mp
86-94 ℃
SMILES string
CN(C)P1Oc2ccc3CCCCc3c2-c4c(O1)ccc5CCCCc45
InChI
1S/C22H26NO2P/c1-23(2)26-24-19-13-11-15-7-3-5-9-17(15)21(19)22-18-10-6-4-8-16(18)12-14-20(22)25-26/h11-14H,3-10H2,1-2H3
InChI key
OIZQADYWBXZQKE-UHFFFAOYSA-N
packaging【包装】
100 mg in clear glass bottle
500 mg in amber glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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