您的位置：首页 > 产品中心 > Anti-Mouse Dnmt3l antibody produced in rabbit
Anti-Mouse Dnmt3l antibody produced in rabbit
| 产品编号： | 3377291 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Mouse Dnmt3l antibody produced in rabbit
Anti-DNA (cytosine-5)-methyltransferase 3-like
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | mouse |
| technique(s) | indirect ELISA: 1:1000 |
| NCBI accession no.【NCBI登记号】 | NP_037501 |
| UniProt accession no.【UniProt登记号】 | Q9UJW3 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
基本信息
| General description【一般描述】 | mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger. |
| Immunogen【免疫原】 | DNMT3L (Q9CWR8, 393-431) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the mouse Dnmt3L sequence within the last 100 aa. The antibody may recognize the human homolog (44 kDa). |
| Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
