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Anti-Mouse IgG (whole molecule)-Agarose antibody produced in goat

产品编号:3377442
规格:affinity isolated antibody, suspension
包装规格:2 ML,5 ML,25 ML
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
33774422 ML2900
33774425 ML4720
337744225 ML16360
基本信息
MDL number
MFCD03791275
NACRES
NA.46
General description【一般描述】
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mice consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases. Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice. Goat Anti-Mouse IgG (whole molecule)-Agarose antibodies bind to all mouse IgG subclasses.
Immunogen【免疫原】
IgG isolated from pooled normal mouse serum
Application【应用】
Soluble antigens from meningococci extracts were mixed with ascitic fluid containing primary antibody and 50 μl of agarose-linked goat anti-mouse IgG for 5 hours at 4 ℃.
Goat Anti-Mouse IgG (whole molecule)-Agarose antibodies have been used for immunoprecipiation assays. The product can also be used for Ouchterlony double diffusion applications.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper)
Immunoprecipitation (1 paper)
Biochem/physiol Actions【生化/生理作用】
IgG helps in opsonization, complement fixation and antibody-dependent cell-mediated cytotoxicity. Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. IgG2a of IgG has cytotropic properties and IgG2 molecules have the ability to activate complement.
Physical form【外形】
Suspension in 0.5 M NaCl containing preservative
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
goat
conjugate【偶联物】
agarose conjugate
antibody form【抗体形式】
affinity isolated antibody
antibody product type
secondary antibodies
clone【克隆】
polyclonal
form【形式】
suspension
species reactivity
mouse
extent of labeling【标记范围】
≥5 mg per mL
technique(s)
Ouchterlony double diffusion: suitable
immunoprecipitation (IP): suitable
matrix【基质】
Cross-linked 4% beaded agarose
matrix activation【基质活化】
cyanogen bromide
matrix spacer【基质隔离区】
1 atom
capacity【容量】
0.4 mg/mL, resin binding capacity (mouse IgG)
storage temp.【储存温度】
2-8℃
packaging【包装】
2, 5, 25 mL in glass bottle
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 3
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