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Anti-MXD4 antibody produced in rabbit
产品别名
Anti-MXD4 antibody produced in rabbit
Anti-MAX dimerization protein 4
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | MXD4 is a basic helix-loop-helix (bHLH) transcription factor that regulates the proliferation of blood precursors during the start of hematopoietic development. Rabbit Anti-MXD4 antibody recognizes canine, bovine, human, mouse, and rat MXD4. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human MXD4 |
| Application【应用】 | Rabbit Anti-MXD4 antibody can be used for western blot applications at a concentration of 0.5 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. |
| Sequence【序列】 | Synthetic peptide located within the following region: SLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNN |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 24 kDa |
| species reactivity | human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_006445 |
| UniProt accession no.【UniProt登记号】 | Q14582 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MXD4(10608) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
