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Anti-MYD88 (ab1) antibody produced in rabbit
产品编号: | 3378925 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-MYD88 (ab1) antibody produced in rabbit
Anti-Myeloid differentiation primary response gene (88)
基本信息
MDL number | MFCD04040473 |
NACRES | NA.41 |
General description【一般描述】 | Myeloid differentiation primary response 88 (MYD88) is a cytosolic soluble adaptor protein. It possesses a toll-interleukin 1 receptor domain and a death domain. The gene encoding this protein is localized on human chromosome 3p22.2. |
Immunogen【免疫原】 | a peptide corresponding to amino acids 233-248 of human MyD88, which differ from mouse by two amino acids. |
Biochem/physiol Actions【生化/生理作用】 | Myeloid differentiation primary response 88 (MYD88) activates innate immune response to Mycobacterium tuberculosis. It is an activator of nuclear factor κ B (NF-κB).The protein mediates the signaling pathways of toll-like and interleukin-1 receptors. Mutation in the gene encoding MYD88 is associated with diffuse large B-cell lymphoma. |
Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP2125. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | predicted mol wt 35 kDa |
species reactivity | human |
technique(s) | immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
UniProt accession no.【UniProt登记号】 | U70451 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... MYD88(4615) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |