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ANTI-NEDD4(C-TERMINAL) antibody produced in rabbit
| 产品编号： | 3379894 |
| 规格： | purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 400 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
ANTI-NEDD4(C-TERMINAL) antibody produced in rabbit
NEDD4-1
KIAA0093
NEDD4
Cell proliferation-inducing gene 53 protein
E3 ubiquitin-protein ligase NEDD4
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (NEDD4) has an amino terminal domain, four tryptophan-rich WW domains and a carboxy-terminal homologous to the E6-AP carboxyl terminus (HECT) ubiquitin ligase domain. The gene encoding this protein is localized on human chromosome 15q21.3. |
| Biochem/physiol Actions【生化/生理作用】 | Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (NEDD4) associates with the PPxY (PY) motifs of the subunits of the human epithelial Na+ channel (hENaC). It is a positive and negative modulator of signaling receptors. The protein is overexpressed in endometrial cancer. |
| Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 149114 Da |
| species reactivity | mouse, human |
| technique(s) | flow cytometry: 1:10-1:50 immunohistochemistry: 1:50-1:100 western blot: 1:1000 |
| NCBI accession no.【NCBI登记号】 | NP_006145.2 |
| UniProt accession no.【UniProt登记号】 | P46934 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NEDD4(4734) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
