您的位置：首页 > 产品中心 > Anti-Nerve Growth Factor Receptor/TNFRSF16 antibody produced in goat
Anti-Nerve Growth Factor Receptor/TNFRSF16 antibody produced in goat
| 产品编号： | 3380002 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Nerve Growth Factor Receptor/TNFRSF16 antibody produced in goat
Anti-p75
Anti-LNGFR
Anti-Tnfrsf16
Anti-Ngfr
基本信息
| MDL number | MFCD00282384 |
| NACRES | NA.41 |
| General description【一般描述】 | Neurotrophins (NT) are growth factors that are essential for the development and maintenance of the nervous system. One of the receptors that mediate the effects of NTs is the Nerve Growth Factor Receptor/TNFRSF16 (p75NGFR, p75NTR). Nerve growth factor (NGF) binds to either to NGF receptor (NGFR) or the Trk receptor and can elicit biological responses through each of the receptors independently. NGFR mediates the effects of NGF that are important in the survival and differentiation of neurons and neural crest-derived cells during embryonic and early postnatal development and maintenance of peripheral neurons. Signaling of NGF through NGFR is also implicated in inflammation and allergic reactions. Expression of NGFR has been associated with favourable prognosis and survival in breast and pancreatic cancers Anti-Nerve Growth Factor Receptor/TNFRSF16 recognizes mouse NGF R. |
| Immunogen【免疫原】 | purified, NSO cell-derived recombinant mouse nerve growth factor receptor extracellular domain. |
| Application【应用】 | Anti-Nerve Growth Factor Receptor/TNFRSF16 antibody may be used for immunoblotting at a working concentration of 2 μg/ml. For immunohistochemistry a working concentration of 5-15 μg/ml is recommended. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | goat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | mouse |
| technique(s) | immunohistochemistry: 5-15 μg/mL western blot: 2 μg/mL |
| UniProt accession no.【UniProt登记号】 | Q9Z0W1 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Ngfr(18053) |
产品说明
| Target description【目标描述】 | Anti-Nerve Growth Factor Receptor/TNFRSF16 recognizes mouse NGF R. Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
