广州伟伯科技有限公司
您的位置:首页 > 产品中心 > Anti-NF-κB p105 antibody produced in rabbit
产品搜索:

Anti-NF-κB p105 antibody produced in rabbit

产品编号:3380117
规格:affinity isolated antibody
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3380117100 μG5040
产品别名

Anti-NF-κB p105 antibody produced in rabbit

EBP-1

NF-κ-B1 p84/NF-κ-B1 p98

NFKB1

DNA-binding factor KBF1

NFKB-p50

基本信息
NACRES
NA.41
General description【一般描述】
Anti-NF-κB p105 Antibody detects endogenous levels of total NF-κB p105 protein.
The gene NFκB1(nuclear factor κ B subunit 1) is mapped to human chromosome 4q24. It codes for NF-κB p105/p50 isoforms.
Immunogen【免疫原】
The antiserum was produced against synthesized peptide derived from human NF-kappaB p105/p50.

Immunogen Range: 874-923
Biochem/physiol Actions【生化/生理作用】
NF-κB (nuclear factor κ B subunit 1) is an important transcription factor that regulates the process of apoptosis, immune response and cell-growth control genes. It is associated with a number of human disorders including inflammatory diseases and cancers. NF-κB signaling cascade is known to be stimulated by many genotoxic stresses and also DNA damage. NF-κB is involved in bone metabolism. Downregulation of NF-κB mediates GPER (G-protein coupled estrogen receptor) specific agonist G-1 induced EMT (epithelial mesenchymal transition) suppression. Thereby, it prevents the motility of triple-negative breast cancer cells in vitro.
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form【外形】
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen 105 kDa
species reactivity
human
concentration【浓度】
~1 mg/mL
technique(s)
ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.【NCBI登记号】
P19838
UniProt accession no.【UniProt登记号】
P19838
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... NFKB1(4790)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.0059