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Anti-NRG3 (center) antibody produced in rabbit

产品编号:3380219
规格:IgG fraction of antiserum, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3380219100 μG4610
产品别名

Anti-NRG3 (center) antibody produced in rabbit

Anti-Neuregulin-3

基本信息
NACRES
NA.41
General description【一般描述】
NRG3, which belongs to the neuregulin family, is a direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. NRG3 does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. The protein exists as an type I membrane protein and as a proteolytically released soluble growth factor form. The membrane-bound form does not appear to be active. NRG3 is highly expressed in most regions of the brain with the exception of corpus callosum, and is expressed at lower level in testis. It is not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes. The NRG3 cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing may involve initial intracellular domain dimerization.
Immunogen【免疫原】
NRG3 (310-346)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human NRG3.
Physical form【外形】
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
IgG fraction of antiserum
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
NCBI accession no.【NCBI登记号】
NP_001010848
UniProt accession no.【UniProt登记号】
P56975
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... NRG3(10718)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
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