Anti-Osteopontin antibody produced in goat

MFCD02263865

NA.41

The OPN (osteopontin) gene is mapped to mouse chromosome 5 E5 and codes for secreted phosphoprotein 1 and is mostly expressed in bone tissue.

purified recombinant mouse osteopontin expressed in NSO cells.

Osteopontin (OPN) serves as a ligand to a number of integrin receptors which are associated with cell motility, chemotaxis, invasion and cell survival. Upregulation of OPN gene is observed in tumors such as colorectal carcinomas, breast cancer and contributes to its pathogenesis. OPN is associated with obesity by mediating adipocyte inflammation and insulin resistance upon macrophage activation. OPN functions as an effector molecule in extracellular signalling and promotes fibrosis and myocyte growth.

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Neutralizes the biological activity of recombinant mouse osteopontin using 293 cells.

200

goat

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

lyophilized powder

mouse

capture ELISA: 0.2-0.8 μg/mL
immunohistochemistry: 5-15 μg/mL using mouse thymus tissue sections
neutralization: 1-3 μg/mL
western blot: 0.1-0.2 μg/mL

P10923

−20℃

mouse ... Spp1(20750)

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13 - Non Combustible Solids

WGK 3