Anti-P2RY14 / P2Y14 antibody produced in rabbit

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human

immunocytochemistry: 5-10 μg/mL
immunohistochemistry: 4 μg/mL

Q15391

dry ice

−20℃

human ... P2RY14(9934)

Caspases mediate essential key proteolytic events in inflammatory cascades and the apoptotic cell death pathway. Caspase 12 is involved in the apoptosis triggered by a stress on the endoplasmic reticulum. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer′s disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase 12 activation results in cell death in the absence of the cytochrome c-dependent pathway. Recently caspase-12 has been suggested to affect signaling pathways linking some G-protein coupled receptors to alphaIIbbeta3 activation. Caspase-12 is ubiquitously expressed in mouse tissues.

Synthetic 20 amino acid peptide from C-terminus of human P2RY14 / P2Y14. Percent identity with other species by BLAST analysis: Human (100%); Monkey (95%).

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Supplied at 1 mg/ml
Solution in phosphate-buffered saline containing less than 0.1% sodium azide.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

12 - Non Combustible Liquids