Anti-PACS2 antibody produced in rabbit

NA.41

Synthetic peptide directed towards the middle region of human PACS2

PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer,PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

Synthetic peptide located within the following region: AHQLPIAEAMLTYKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDD

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

98 kDa

rat, dog, horse, human, bovine, guinea pig, mouse

0.5 mg - 1 mg/mL

western blot: suitable

NM_015197

Q86VP3

wet ice

−20℃

human ... PACS2(23241)

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12 - Non Combustible Liquids

WGK 3