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Anti-PARG (C-term) antibody produced in rabbit
| 产品编号： | 3382461 |
| 规格： | saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-PARG (C-term) antibody produced in rabbit
Anti-Poly(ADP-ribose) glycohydrolase
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | PARG (Poly ADP-ribose glycohydrolase) is a catabolic enzyme with molecular mass ranging from 60-74kDa. It has four isoforms namely G1, G2, G3 and G4 with high protease sensitivity. |
| Immunogen【免疫原】 | PARG (NP_003622, 395-431) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human Parg. |
| Application【应用】 | Anti-PARG (C-term) antibody produced in rabbit is suitable for immunohistochemistry (1:50-1:100),indirect ELISA (1:1000) and western blot (1:100-1:500) applications. |
| Biochem/physiol Actions【生化/生理作用】 | PARG (Poly ADP-ribose glycohydrolase) is involved in several gene regulation processes such as maintenance of chromatin structure, transcription, DNA repair and apoptosis. It regulates retinoic acid receptor (RAR)-mediated transcription during chromatin remodeling. It catabolically separate ADP-ribose polymers synthesized by poly-(ADP-ribose) polymerases. A study shows that PARG plays a therapeutic role in various physiological conditions such as inflammation, ischemia, stroke, and cancer chemotherapy. |
| Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunohistochemistry: 1:50-1:100 indirect ELISA: 1:1000 western blot: 1:100-1:500 |
| NCBI accession no.【NCBI登记号】 | NP_003622 |
| UniProt accession no.【UniProt登记号】 | Q86W56 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PARG(8505) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
