Anti-PARP1 antibody produced in rabbit

NA.41

Synthetic peptide directed towards the C terminal region of human PARP1

PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.

Synthetic peptide located within the following region: ISRLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVIDTSLLYN

rabbit

100

unconjugated

IgG fraction of antiserum

primary antibodies

polyclonal

113 kDa

bovine, horse, mouse, human, dog, rabbit, rat, guinea pig

pkg of 100 μL buffered aqueous solution
pkg of 100 μg lyophilized powder

0.5 mg - 1 mg/mL

western blot: suitable

NP_001609

P09874

−20℃

human ... PARP1(142)

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12 - Non Combustible Liquids

WGK 3