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Anti-PAWR (AB1) antibody produced in rabbit
产品别名
Anti-PAWR (AB1) antibody produced in rabbit
Anti-PRKC, apoptosis, WT1, Regulator
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | PAWR is a transcriptional repressor that has a leucine zipper domain. Genetic variations in PAWR have been linked to major depressive disorder (MDD) and schizophrenia. Rabbit Anti-PAWR (AB1) antibody recognizes canine, human, mouse, and rat PAWR. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human PAWR |
| Application【应用】 | Rabbit Anti-PAWR (AB1) antibody can be used for western blot applications at a concentration of 1μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells. |
| Sequence【序列】 | Synthetic peptide located within the following region: VNIPAAECLDEYEDDEAGQKERKREDAITQQNTIQNEAVNLLDPGSSYLL |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 37 kDa |
| species reactivity | rat, horse, human, mouse, guinea pig |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_002574 |
| UniProt accession no.【UniProt登记号】 | O75796 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PAWR(5074) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
