Anti-PDCD1 (AB1) antibody produced in rabbit

NA.41

Programmed cell death protein 1 (PDCD1) is part of the cluster of differentiation 28 (CD28) superfamily. It interacts with its ligands, that is, programmed death ligand-1 and -2 (PD-L1/PD-L2). The gene encoding this protein is localized to human chromosome 2q37.

Synthetic peptide from human PDCD1 / CD279.

Programmed cell death protein 1 (PDCD1) plays an important role in the immune regulation by acting as a negative co-stimulatory factor. It suppresses the functions and multiplication of T cells, thereby reducing the release of IL-2 (interleukin-2), IL-10 and IFN-γ (interferon γ). In the presence of tumor microenvironment, PDCD1 along with its ligand modulates T effector functioning, thereby protecting cancer cells from immune-associated rejection. Mutation in this gene is associated with symptoms and progression of multiple sclerosis and susceptibility to systemic lupus erythematosus.

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Solution in phosphate-buffered saline containing 0.02% sodium azide.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

mouse, human, rat

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

Q15116

−20℃

human ... PDCD1(5133)

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12 - Non Combustible Liquids