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抗-磷酸化-Caspase 8 (pTyr380) 兔抗
Anti-phospho-Caspase 8 (pTyr380) antibody produced in rabbit
产品别名
抗-磷酸化-Caspase 8 (pTyr380) 兔抗
Anti-phospho-Caspase 8 (pTyr380) antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Caspase-8 (CASP8) is a member of the cysteine aspartate-specific proteases family. It is produced in the cell as procaspase-8, a sluggish zymogen. Procaspase-8 has a long prodomain, carrying two major protein interaction domains, DED1 and DED2, followed by one large (p18) and one small (p10) catalytic subunit. CASP8 is mapped to human chromosome 2q33. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human Caspase 8 around the phosphorylation site of Tyr380. Immunogen Range: 346-395 |
| Biochem/physiol Actions【生化/生理作用】 | Caspase-8 (CASP8) is involved in apoptosis, inflammation and cellular differentiation. It activates programmed cell death, after death receptor ligation. Casp8 is essential for the clonal expansion of T and B cell. It also participates in lymphocyte homeostasis. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 55 kDa |
| species reactivity | human, rat, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q14790 |
| UniProt accession no.【UniProt登记号】 | Q14790 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CASP8(841) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
