Anti-phospho-CAV1 (pTyr¹⁴) antibody produced in rabbit

NA.41

Peptide sequence around phosphorylation site of tyrosine 14 (H-L-Y(p)-T-V), according to the protein CAV1.

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

rabbit

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

~24 kDa

human, mouse, rat

1 mg/mL

indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

IgG

(H-L-YP-T-V)

NP_001166366.1

Q03135

wet ice

−20℃

human ... CAV1(857)

The scaffolding protein encoded by Caveolin-1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.

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10 - Combustible liquids

WGK 1