您的位置：首页 > 产品中心 > Anti-phospho-NF2 (pSer518) antibody produced in rabbit
Anti-phospho-NF2 (pSer518) antibody produced in rabbit
产品别名
Anti-phospho-NF2 (pSer518) antibody produced in rabbit
Anti-BANF antibody produced in rabbit
Anti-SCH antibody produced in rabbit
Anti-neurofibromin 2 (merlin) antibody produced in rabbit
Anti-ACN antibody produced in rabbit
基本信息
| MDL number | MFCD03845618 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of serine 518 (R-L-S(p)-M-E), according to the protein NF2. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~69 kDa |
| species reactivity | mouse, human, rat |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (R-L-SP-M-E) |
| NCBI accession no.【NCBI登记号】 | NP_000259.1 |
| UniProt accession no.【UniProt登记号】 | P35240 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NF2(4771) |
产品说明
| Target description【目标描述】 | Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
