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Anti-phospho-SNCA (pTyr125) antibody produced in rabbit
产品别名
Anti-phospho-SNCA (pTyr125) antibody produced in rabbit
Anti-PARK1 antibody produced in rabbit
Anti-NACP antibody produced in rabbit
Anti-MGC110988 antibody produced in rabbit
Anti-PARK4 antibody produced in rabbit
Anti-synuclein, alpha (non A4 component of amyloid precursor) antibody produced in rabbit
基本信息
| MDL number | MFCD02095740 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of tyrosine 125 (E-A-Y(p)-E-M), according to the protein SNCA. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~18 kDa |
| species reactivity | human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (E-A-YP-E-M) |
| NCBI accession no.【NCBI登记号】 | NP_000336.1 |
| UniProt accession no.【UniProt登记号】 | P37840 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SNCA(6622) |
产品说明
| Target description【目标描述】 | SncA is a member of the synuclein family of structurally related proteins that are prominently expressed in the central nervous system, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and SncA and Snc-Beta inhibit phospholipase D2 selectively. SncA may serve to integrate presynaptic signaling and membrane trafficking. Aggregated SncA proteins form brain lesions that are hallmarks of neurodegenerative synucleinopathies. Defects in SncA play a role in the pathogenesis of Parkinson disease. SncA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer disease. SncA shares 95% sequence homology with rat SncA. Rat SncA is specifically expressed in brain and is associated with synaptosomal membranes in neurons. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
