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Anti-PLK2 antibody produced in rabbit
产品别名
Anti-PLK2 antibody produced in rabbit
PLK-2
Serum-inducible kinase
Serine/threonine-protein kinase SNK
Polo-like kinase 1
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Polo-like kinases 2 (PLK2) is a member of the serine-threonine kinases family. The PLK2 gene is mapped to human chromosome 5q11.2. PLK2 comprises a C-terminal polo-box domain (PBD) devoid of catalytic activity and an N-terminal kinase domain. Anti-PLK2 Antibody detects endogenous levels of total PLK2 protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human PLK2. Immunogen Range: 291-340 |
| Application【应用】 | Anti-PLK2 antibody produced in rabbit has been used in western blotting(1:1000) (1:5000) |
| Biochem/physiol Actions【生化/生理作用】 | Polo-like kinase 2 (PLK2) participates in regulating centriole duplication, cell death, and cell cycle. It also mediates the spine-associated RapGAP (SPAR) degradation via the ubiquitin-proteasome pathway, thereby regulating synaptic plasticity. Mutations in the PLK2 gene are observed in colorectal cancers. The PLK2 gene knockdown leads to defects in centriole duplication. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 78 kDa |
| species reactivity | mouse, rat, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:40000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q9NYY3 |
| UniProt accession no.【UniProt登记号】 | Q9NYY3 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PLK2(10769) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
