Anti-POLR2A antibody produced in rabbit

NA.41

RNA polymerase II subunit A (POLR2A) gene with 29 exons is mapped on human chromosome 17p13.1. This gene codes for a catalytic subunit of RNA polymerase II. The encoded protein consists of a highly conserved 5′ flanking region.

peptide corresponding to the N-terminal region of human POLR2A, conjugated to KLH. The corresponding sequence is identical in mouse, rat, monkey, bovine, dog and pig.

RNA polymerase II subunit A (POLR2A) catalyzes the synthesis of messenger RNA in eukaryotes. The 5′ flanking domain of RNA polymerase II subunit A (POLR2A) plays a vital role in transcriptional regulation. Mutation in the gene is associated with the pathogenesis of meningiomas.

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

rabbit

unconjugated

Ig fraction of antiserum

primary antibodies

polyclonal

buffered aqueous solution

antigen ~250 kDa

human

immunoprecipitation (IP): 5-10 μL using whole extract of human HeLa cells
indirect immunofluorescence: 1:400-1:800 using human HeLa cells
western blot: 1:2000-1:4000 using nuclear extracts of HeLa cells

P24928

dry ice

−20℃

human ... POLR2A(5430)
mouse ... Polr2a(20020)
rat ... Polr2a(363633)

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

12 - Non Combustible Liquids

WGK 2