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Anti-POLR2B (AB2) antibody produced in rabbit
产品别名
Anti-POLR2B (AB2) antibody produced in rabbit
Anti-Polymerase (RNA) II (DNA directed) Polypeptide B, 140 kDa
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | POLR2B is a subunit of the RNA polymerase II that synthesises mRNA in cells. This subunit links DNA, nascent mRNA and the enzyme active site during transcription. Rabbit Anti-POLR2B antibody recognizes human, mouse, rat, canine, bovine, and chicken POLR2B. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human POLR2B |
| Application【应用】 | Rabbit Anti-POLR2B (AB2) antibody can be used for western blot applications at a concentration of 5μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | POLR2B is the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA. |
| Sequence【序列】 | Synthetic peptide located within the following region: TYSAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTD |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 134 kDa |
| species reactivity | rabbit, horse, dog, mouse, rat, guinea pig, human, bovine |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_000929 |
| UniProt accession no.【UniProt登记号】 | P30876 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... POLR2B(5431) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
