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Anti-Potassium Channel K2P4.1 (TRAAK) 兔抗
Anti-Potassium Channel K2P4.1 (TRAAK) antibody produced in rabbit
| 产品编号： | 3387469 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 50 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Potassium Channel K2P4.1 (TRAAK) 兔抗
Anti-Potassium Channel K2P4.1 (TRAAK) antibody produced in rabbit
Anti-TWIK-related arachidonic acid-stimulated K+ channel
Anti-KCNK4
基本信息
| MDL number | MFCD09753858 |
| NACRES | NA.41 |
| General description【一般描述】 | The gene K2P4.1, also referred to as KCNK4 (potassium two pore domain channel subfamily K member 4), encodes a protein belonging to the subfamily of K2P (two pore domain K+ channel) channels called TRAAK (TWIK-related arachidonic acid-stimulated K+ channel). The TRAAK channels are expressed selectively in the nervous system. TRAAK channel contains two protomers, each with two distinct pore domains forming a two-fold symmetric potassium channel. |
| Specificity【特异性】 | The K2P4.1 antibody is directed against a highly conserved epitope in the intraracellular C-terminal region of the human K2P4.1 channel. |
| Immunogen【免疫原】 | peptide NLAFIDESSDTQSERGC, corresponding to amino acid residues 343-359 of human K2P4.1. |
| Biochem/physiol Actions【生化/生理作用】 | The gene KCNK4 (potassium two pore domain channel subfamily K member 4) encodes a potassium channel that is mechanosensitive and is regulated by polyunsaturated fatty acids and temperature. The structure and chemical composition of the lipid bilayer has a profound effect on the functioning of this K+ channel. It is found to regulate the noxious input threshold in dorsal root ganglia neurons. |
| Physical form【外形】 | Lyophilized powder from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.025% sodium azide. |
| Reconstitution【重悬】 | Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein, such as BSA (1-3%). |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | rat, human |
| technique(s) | immunohistochemistry: suitable western blot: 1:200 using HEK-K2P4.1 transfected cells or rat cerebellum lysate |
| UniProt accession no.【UniProt登记号】 | Q9NYG8 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... KCNK4(50801) rat ... Kcnk4(116489) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
