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Anti-Potassium Channel KV11.3 (erg3) 兔抗
Anti-Potassium Channel Kv11.3 (erg3) antibody produced in rabbit
| 产品编号： | 3387474 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 50 μL，200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Potassium Channel KV11.3 (erg3) 兔抗
Anti-Potassium Channel Kv11.3 (erg3) antibody produced in rabbit
Anti-ether-a-go-go-related channel 3
Anti-KCNH7
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The gene Kcnh7 (potassium voltage-gated channel subfamily H member 7), also referred to as erg3, encodes a subunit of ether-à-go-go related (erg) K+ channels. The erg K+ channels are part of the EAG (ether-à-go-go) family of voltage-gated K+ channels. The encoded protein is found to be expressed in the apical membrane of the retinal pigment epithelium. |
| Specificity【特异性】 | The KV11.3 antibody is directed against an intracellular epitope of C-terminal part of KV11.3. |
| Immunogen【免疫原】 | synthetic peptide CPEFLDLEKSKLKSKE corresponding to amino acids 1108-1123 of rat KV11.3. |
| Biochem/physiol Actions【生化/生理作用】 | The gene Kcnh7 (potassium voltage-gated channel subfamily H member 7) encodes a voltage gated K+ channel that modulates the membrane potential in its rested and activated state. In the nervous system, it may participate in the regulation of neuronal excitability. The erg3 channels have relatively negative activation threshold compared to erg1 and erg2. They are capable of recycling K+ ions to the subretinal space in the dark and contribute to the maintenance of the resting membrane potential. |
| Physical form【外形】 | Lyophilized powder containing phosphate buffered saline, pH 7.4, 1% BSA and 0.025% sodium azide. |
| Reconstitution【重悬】 | Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%). |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | mouse, human, rat |
| technique(s) | immunohistochemistry: suitable using rat brain sections western blot: 1:300 using rat brain lysates |
| UniProt accession no.【UniProt登记号】 | Q9NS40 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... KCNH7(90134) mouse ... Kcnh7(170738) rat ... Kcnh7(170739) |
