您的位置：首页 > 产品中心 > 抗-钾通道 Kv4.3 兔抗
抗-钾通道 Kv4.3 兔抗
Anti-Potassium Channel Kv4.3 antibody produced in rabbit
| 产品编号： | 3387479 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 0.05 ML，0.2 ML |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
抗-钾通道 Kv4.3 兔抗
Anti-Potassium Channel Kv4.3 antibody produced in rabbit
基本信息
| MDL number | MFCD02097221 |
| NACRES | NA.41 |
| General description【一般描述】 | Potassium voltage-gated channel subfamily D member 3 (KCND3) gene codes for Kv4.3, an α-subunit of the Ito channel. It has seven exons and is mapped to the human chromosome 1p13.2. Kv4.3 is expressed in the brain and the heart. Anti-potassium channel Kv4.3 recognizes Kv4.3 protein in the rat by immunoblotting. |
| Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 451-468 of rat or human potassium channel Kv4.3 (with additional N-terminal tyrosine and methionine replaced with norleucine). |
| Application【应用】 | Anti-Potassium Channel Kv4.3 antibody produced in rabbit has been used in immunohistochemistry. |
| Biochem/physiol Actions【生化/生理作用】 | Potassium channels contribute to maintaining cell volume, neuronal excitability, and the secretion of transmitters, salt, and hormones. Potassium voltage-gated channel subfamily D member (Kv4.3) is involved in membrane repolarization in excitable cells. Kv4.3 may participate in the development of the cerebellum. It is capable of forming homo- or hetero-tetramers with the Shal subfamily channel members. KCND3 gene mutations result in Brugada syndrome and spinocerebellar ataxia type 22. |
| Physical form【外形】 | Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.025% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | human, rat |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable western blot (chemiluminescent): 1:200 |
| UniProt accession no.【UniProt登记号】 | Q9UK17 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... KCND3(3752) rat ... Kcnd3(65195) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H312 + H332 - H412 |
| Precautionary Statements | P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3 |
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
