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Anti-Potassium Channel sloβ2 (KCNMB2) 兔抗
Anti-Potassium Channel sloβ2 (KCNMB2) antibody produced in rabbit
| 产品编号： | 3387481 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 50 μL，200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Potassium Channel sloβ2 (KCNMB2) 兔抗
Anti-Potassium Channel sloβ2 (KCNMB2) antibody produced in rabbit
Anti-BKCa β subunit 2
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | peptide (C)RHDEKRNIYQKIRDHDLLD, corresponding to amino acid residues 14-32 of human sloβ2. |
| Physical form【外形】 | Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.025% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | mouse, canine, rat |
| technique(s) | immunohistochemistry: suitable using rat brain sections western blot: 1:200 using rat kidney and heart samples |
| UniProt accession no.【UniProt登记号】 | Q811Q0 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | rat ... Kcnmb2(294961) |
产品说明
| Target description【目标描述】 | The sloβ2 subunit is unique because it is able to induce a rapid and complete inactivation of the KCa1.1 channel in a manner that closely resembles the ball-and-chain inactivation of the voltage-dependent K+ (Kv) channels.The inactivation is dependent on a sequence in the N-terminal part of the sloβ2 subunit that appears to block the mouth of the ion permeation pathway. sloβ2 subunit appears to participate in the inactivation of the KCa1.1 channel in hippocampal CA1 neurons and adrenal chromaffin cells. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
