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Anti-POU3F2 (AB2) antibody produced in rabbit
产品别名
Anti-POU3F2 (AB2) antibody produced in rabbit
Anti-7-Oct
Anti-BRN2
Anti-POU domain, class 3, transcription factor 2
Anti-POUF3
Anti-OTF7
基本信息
NACRES | NA.41 |
General description【一般描述】 | POU3F2 is a neural transcription factor that modulates the differentiation of neurons and facilitates corticotropin-releasing hormone regulated gene stimulation. POU3F2 has been implicated in melanoma. Rabbit Anti-POU3F2 (AB2) antibody recognizes bovine, canine, human, mouse, and rat POU3F2. |
Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human POU3F2 |
Application【应用】 | Rabbit Anti-POU3F2 (AB2) antibody can be used for western blot applications at 0.5μg/ml. |
Biochem/physiol Actions【生化/生理作用】 | N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176), and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM]. |
Sequence【序列】 | Synthetic peptide located within the following region: LGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPPPPPPQGPPG |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 47 kDa |
species reactivity | mouse, rat, bovine, guinea pig, dog, human |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | immunohistochemistry: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_005595 |
UniProt accession no.【UniProt登记号】 | P20265 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... POU3F2(5454) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |