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Anti-PPFIA1 (ab1) antibody produced in chicken
产品编号: | 3387681 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-PPFIA1 (ab1) antibody produced in chicken
Anti-LIP.1
Anti-LIP1
Anti-LAR-interacting protein 1
Anti-LIPA1_HUMAN
Anti-LIPRIN
Anti-Liprin-α-1
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Recombinant PTPRF interacting protein α 1 isoform b Immunogen Sequence: GI # 4505983, sequence 310-360 |
Application【应用】 | Anti-PPFIA1 (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. |
Biochem/physiol Actions【生化/生理作用】 | Liprin-α-1 is a cytoplasmic 160kDa phosphoserine protein encoded by the PPFIA1 gene in humans. It encodes liprin α, a protein involved in cell adhesion, integrin expression and cell-matrix interactions. PPFIA1 may act as a potential functional candidate for acute lung injury risk gene for future research. It is frequently co-amplified with the Cyclin D1 gene in oral carcinomas and may present a biomarker as well as a novel target for specific gene therapy. Liprin′s function is to localize LAR family tyrosine phosphatases at specific sites on the plasma membrane. It may help in regulating their interaction with the extracellular environment and their associations with substrates. PPFIA1 may regulate the disassembly of focal adhesions and help to orchestrate cell-matrix interactions. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
biological source【生物来源】 | chicken |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | rat, mouse, human |
manufacturer/tradename | Genway 15-288-21470 |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_003617.1 |
UniProt accession no.【UniProt登记号】 | Q13136 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... PPFIA1(8500) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |