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Anti-Prmt1 antibody produced in rabbit
| 产品编号： | 3388461 |
| 规格： | ~1 mg/mL, affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Prmt1 antibody produced in rabbit
Anti-Protein Arginine Methyl Transferase 1 (NQ-15)
基本信息
| MDL number | MFCD04975120 |
| NACRES | NA.41 |
| General description【一般描述】 | PRMT1 belongs to the family of protein arginine methyl transferases (PRMT). These enzymes transfer the methyl group from S-adenosyl-L methionine to the guanidino nitrogen atoms of an arginine residue. PRMTs are divided in two major types, I and II. It is also known as HRMT1L2 and IR1B4. PRMT1 was isolated through its interaction with BTG1 and TIS2, proteins that are important in cell quiescence. It is a 361 amino acids protein; its splicing variants differ at the N-terminus, giving rise to three isoforms (variants 1, 2 and 3). |
| Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 326-341 of mouse PRMT1, conjugated to KLH via an N-terminal added cysteine residue. The sequence is conserved in human, and differs by one amino acid from the rat sequence. |
| Application【应用】 | Anti-PRMT1 antibody produced in rabbit has been used in immunoblotting. |
| Biochem/physiol Actions【生化/生理作用】 | PRMT type 1 and 2 catalyze the formation of monomethylarginine, but differs in that Type I (including PRMT1, 3, 4, and 6) catalyzes the formation of asymmetric dimethylarginine, whereas type II (PRMT5) catalyzes the formation of symmetric dimethylarginine. |
| Physical form【外形】 | 0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。 |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~42 kDa |
| species reactivity | human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | indirect immunofluorescence: 2.5-5.0 μg/mL using paraformaldehyde-fixed 293T cells microarray: suitable western blot: 0.25-0.5 μg/mL using 293T cell extracts |
| UniProt accession no.【UniProt登记号】 | Q99873 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PRMT1(3276) mouse ... Prmt1(15469) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
