您的位置：首页 > 产品中心 > Anti-PRMT1 antibody, Mouse monoclonal
Anti-PRMT1 antibody, Mouse monoclonal
| 产品编号： | 3388462 |
| 规格： | clone PRMT1-171, purified from hybridoma cell culture |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-PRMT1 antibody, Mouse monoclonal
Anti-Protein-Arginine Methyl Transferase 1
基本信息
| MDL number | MFCD04975120 |
| General description【一般描述】 | Protein arginine methyltransferase 1 (PRMT1) gene is localized on human chromosome 19q13.33. It is part of the type I PRMT family. |
| Specificity【特异性】 | Does not cross-react with PRMT2, 3, 4, and 5. |
| Immunogen【免疫原】 | full length PRMT1. Does not cross-react with PRMT2, 3, 4, and 5. |
| Application【应用】 | Anti-PRMT1 antibody, Mouse monoclonal has been used for Immunofluorescence and Western Blotting. |
| Biochem/physiol Actions【生化/生理作用】 | Protein arginine methyltransferase 1 (PRMT1) is crucial for the formation of asymmetric dimethylarginine. It can methylate Twist-1, a transcription factor. The protein also methylates histones and thus modulates transcription and protein activity. PRMT1 is involved in epithelial-mesenchymal transition and may have a role in cancer. |
| Physical form【外形】 | 0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。 |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | PRMT1-171, monoclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~42 kDa |
| species reactivity | canine, monkey, hamster, bovine, human, mouse, rat, chicken |
| concentration【浓度】 | ~2 mg/mL |
| technique(s) | immunoprecipitation (IP): suitable indirect ELISA: suitable western blot: 2 μg/mL using whole cell extract of 293T cells |
| isotype【同位素/亚型】 | IgG1 |
| UniProt accession no.【UniProt登记号】 | Q99873 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PRMT1(3276) |
| packaging【包装】 | 200 μL in glass insert |
产品说明
| Storage and Stability【储存及稳定性】 | For continuous use, store at 2-8 C for up to one month. For prolonged storage, freeze in working aliquots at 20 C. Repeated freezing and thawing, or storage in frost-free freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
