Anti-QSOX2 antibody produced in rabbit

HPA012716    Human Protein Atlas characterization data

The gene encoding quiescin Q6 sulfhydryl oxidase 2 (QSOX2) contains 12 exons and is localized to chromosome 9q34.3. It belongs to the sulfhydryl oxidase/Quiescin6 family. QSOX2 contains a signal sequence, a protein-disulfide-isomerase-type thioredoxin domain and yeast essential for respiration and vegetative growth protein 1 (ERV1) domain. It is expressed in the plasma and nuclear membrane.

Sulfhydryl oxidase 2 precursor recombinant protein epitope signature tag (PrEST)

Anti-QSOX2 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige. Anti-QSOX2 antibody produced in rabbit can also be used for immunocytochemistry.

Quiescin Q6 sulfhydryl oxidase 2 (QSOX2) catalyzes the oxidation of sulfhydryl groups of thiols in peptides and proteins to disulfides, with the reduction of molecular oxygen to hydrogen peroxide. It plays a major role in sensitization of neuroblastoma cells to interferon gamma (IFN-γ)-induced apoptosis.

Prestige Antibodies^® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies^® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

• IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
• Protein array of 364 human recombinant protein fragments.

Corresponding Antigen APREST72164.

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Prestige Antibodies is a registered trademark of sigma-aldrich Co. LLC

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

Prestige Antibodies^® Powered by Atlas Antibodies

buffered aqueous glycerol solution

human

antibody small pack of 25 μL

RNAi knockdown
Learn more about Antibody Enhanced Validation

immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:200-1:500

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Q6ZRP7

wet ice

−20℃

human ... QSOX2(169714)

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12 - Non Combustible Liquids

WGK 1

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)