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Anti-RGS7 antibody produced in chicken

产品编号:3391617
规格:affinity isolated antibody, buffered aqueous solution
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
339161750 μG4330
产品别名

Anti-RGS7 antibody produced in chicken

Anti-Regulator of G-protein signaling 7

产品性质
biological source【生物来源】
chicken
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
mouse, human, rat
manufacturer/tradename
Genway 15-288-21310
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_002915.1
UniProt accession no.【UniProt登记号】
P49802
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... RGS7(6000)
基本信息
General description【一般描述】
RGS7 (regulator of G-protein signaling 7) is a member of the R7 subfamily of RGS superfamily of regulators, and shares high homology with RGS9-2. It is composed of the catalytic RGS domain, a dishevelled, EGL-10 and pleckstrin (DEP) domain in its N-terminal, along with a G protein γ subunit-like (GGL) domain. It is both a soluble cytosolic protein as well as a membrane protein.
Immunogen【免疫原】
Immunogen Sequence: GI # 11140809, sequence 227-262
Recombinant regulator of G-protein signalling 7
Application【应用】
Anti-RGS7 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions【生化/生理作用】
Regulator of G-protein signaling 7 belongs to a subfamily of regulator of G protein signaling (RGS) proteins, which modulate G protein signaling by acting as GTPase-activating proteins for G protein α-subunits. RGS7 exists as a dimer with the G protein β(5)-subunit. It plays a major role in the pathogenesis of panic disorder (PD). RGS7 has a potential role in neurons communicating between classical heterotrimeric G protein subunits and/or their effectors at the plasma membrane and the cell nucleus. It helps in regulating signaling by μ-opioid receptor (MOR) and dopamine D2 receptor (D2R) and are implicated in drug addiction, movement disorders and nociception.
Physical form【外形】
Solution in phosphate buffered saline containing 0.02% sodium azide.
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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