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Anti-RNF2 (AB2) antibody produced in rabbit
产品别名
Anti-RNF2 (AB2) antibody produced in rabbit
Anti-ring finger protein 2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | RNF2 is a polycomb group protein that modulates the transcriptional repression of developmental and cell proliferation genes. Studies have reported that Rnf2 deficiency causes gastrulation arrest and inhibits cell cycle progression. Rabbit Anti-RNF2 antibody recognizes canine, zebrafish, chicken, bovine, human, mouse, rat, and pig RNF2. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human RNF2 |
| Application【应用】 | Rabbit Anti-RNF2 (AB2) antibody can be used for western blot applications at a concentration of 1.25 μg/ml. It can also be used for IHC applications at a concentration of 4-8 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. |
| Sequence【序列】 | Synthetic peptide located within the following region: LVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGE |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 29 kDa |
| species reactivity | horse, dog, rat, human, guinea pig, bovine, mouse, rabbit |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_009143 |
| UniProt accession no.【UniProt登记号】 | Q5TEN1 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... RNF2(6045) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
