您的位置：首页 > 产品中心 > Anti-RNF4 (176-190) antibody produced in rabbit
Anti-RNF4 (176-190) antibody produced in rabbit
| 产品编号： | 3392284 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-RNF4 (176-190) antibody produced in rabbit
Anti-Ring finger protein 4
Anti-RES4-26
Anti-SNURF
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Really interesting new gene (RING ) finger protein 4 (RNF4) gene encodes ubiquitin E3 ligase, an enzyme widely expressed in many tissues. The protein contains a RING (really interesting new gene) finger domain and around three small ubiquitin-related modifier (SUMO)-interaction motifs. RNF4 is mapped to human chromosome 4p16.3. |
| Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 176-190 of human RNF4 |
| Application【应用】 | Anti-RNF4 (176-190) antibody produced in rabbit has been used in western blotting analysis. |
| Biochem/physiol Actions【生化/生理作用】 | Really interesting new gene (RING ) finger protein 4 (RNF4) catalyzes the ubiquitylation of proteins associated with small ubiquitin-related modifier (SUMO). Rnf4 is involved in DNA repair, in transcription and chromatin regulation. It is also associated with the process of hematopoiesis. RNF4 is implicated in acute promyelocytic leukemia, acute myeloid leukemia, Fanconi anemia and aplastic anemia. |
| Physical form【外形】 | 0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。 |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~21 kDa |
| species reactivity | human |
| technique(s) | western blot: 1:500-1:2,000 |
| UniProt accession no.【UniProt登记号】 | P78317 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... RNF4(6047) |
产品说明
| Target description【目标描述】 | RNF4 (176-190), ring finger protein 4. encodes a protein that contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
