ANTI-RUNX2 antibody produced in mouse

100

mouse

unconjugated

purified immunoglobulin

primary antibodies

6E1, monoclonal

buffered aqueous solution

antigen 36.74 kDa

human

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL

IgG2b

NM_004348

Q13950

dry ice

−20℃

human ... RUNX2(860)

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. (provided by RefSeq)

RUNX2 (NP_004339, 251 a.a. ~ 350 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
NPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQAGA

Solution in phosphate buffered saline, pH 7.4

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12 - Non Combustible Liquids