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Anti-Seasonal H1N1 Neuraminidase antibody produced in rabbit
产品编号: | 3393987 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Seasonal H1N1 Neuraminidase antibody produced in rabbit
Anti-NA
Anti-Seasonal Influenza A (H1N1) Neuraminidase
Anti-Influenza N1
Anti-Flu N1
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | viral |
technique(s) | indirect ELISA: suitable |
NCBI accession no.【NCBI登记号】 | ACA33620 |
UniProt accession no.【UniProt登记号】 | B1AGS8 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
基本信息
Immunogen【免疫原】 | Neuraminidase antibody was raised against a synthetic peptide from the seasonal influenza (H1N1) Neuraminidase protein. This antibody is a cognate pair with product SAB3500066. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP3500065. |
Physical form【外形】 | Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
产品说明
Target description【目标描述】 | Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States (2). The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic (3). Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin (4). The distinct antigenic properties of the new swine influenza virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups (5). This antibody is specific for Neuraminidase from the seasonal influenza (H1N1) and will not recognize the corresponding Neuraminidase sequence from the swine-origin influenza virus (A/California/14/2009 (H1N1)). |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |