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Anti-SerPINE1 (AB2) antibody produced in rabbit
产品别名
Anti-SerPINE1 (AB2) antibody produced in rabbit
Anti-PLANH1
Anti-PAI1
Anti-Serpin peptidaSe inhibitor, clade E , member 1
Anti-PAI
Anti-PAI-1
基本信息
| MDL number | MFCD00164749 |
| NACRES | NA.41 |
| General description【一般描述】 | SerPINE1 is a serine proteinase inhibitor that blocks fibrinolys by inhibiting tissue plasminogen activator (tPA) and urokinase (uPA). Genetic variations in SERPINE1 have been linked to pre-eclampsia (PE). Studies have reported that targeting SERPINE1 (PAI-1) expression in Alzheimer′s disease may have therapeutic implications. Moreover, MiR-34c regulates SERPINE1 expression in emphysema. Rabbit Anti-SerPINE1 antibody recognizes human, mouse, rat, zebrafish, bovine, pig, chicken, and canine SERPINE1. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human SERPINE1 |
| Application【应用】 | Rabbit Anti-SerPINE1 antibody is suitable for western blot applications at a concentration of 0.5 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | SERPINE1 acts as ′bait′ for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. |
| Sequence【序列】 | Synthetic peptide located within the following region: VNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVM |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 43 kDa |
| species reactivity | rat, pig, bovine, human, horse, sheep, dog, rabbit |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_000593 |
| UniProt accession no.【UniProt登记号】 | P05121 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SERPINE1(5054) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
