Anti-SLC1A1 antibody produced in rabbit

NA.41

SLC1A1 (also known as EAAC1, EAAT3) is localized at the postsynaptic site of neurons. It is expressed at moderate levels in the adult brain, mainly in the hippocampus, basal ganglia and olfactory bulb and is considered to make a minor contribution to glutamate removal from the synapse.

synthetic peptide corresponding to a sequence near the C-terminus of human SLC1A1, conjugated to KLH. The corresponding sequence is identical in mouse and rat SLC1A1.

Anti-SLC1A1 antibody produced in rabbit has been used in immunohistochemistry and immunoblotting.

SLC1A1 regulates the developmental effects of glutamate. It is highly regulated by neural activity and intracellular signaling pathways involving mainly PKCa, PI3K, and glial factors, resulting in rapid changes in the trafficking of the transporter and in its membrane location.

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

antigen ~70 kDa

mouse, human

recombinant expression
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~1.0 mg/mL

immunohistochemistry: 10-20 μg/mL using formalin-fixed paraffin-embedded human small intestine.
western blot: 1.5-3.0 μg/mL using Neuro-2a cell extracts.

P43005

dry ice

−20℃

human ... SLC1A1(6505)
mouse ... Slc1a1(20510)
rat ... Slc1a1(25550)

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