您的位置：首页 > 产品中心 > Anti-SNF1LK antibody produced in rabbit
Anti-SNF1LK antibody produced in rabbit
产品别名
Anti-SNF1LK antibody produced in rabbit
Anti-msk
Anti-SIK
Anti-SNF1-like kinase
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | SNF1-like kinase (SNF1LK, MSK, SIK), a class II HDAC kinase, promotes survival of skeletal myocytes and may function in cell cycle regulation at the level of G2/M transition. |
| Specificity【特异性】 | Anti-SNF1LK polyclonal antibody reacts with bovine, human, mouse, rat, chicken, and canine SNF1-like kinases. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human SNF1LK |
| Application【应用】 | Anti-SNF1LK polyclonal antibody is used to tag SNF1-like kinase for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of SNF1-like kinase in cell survival and cell cycle regulation. |
| Biochem/physiol Actions【生化/生理作用】 | SNF1LK play a transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. It also plays a potential role in G2/M cell cycle regulation. It inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3. |
| Sequence【序列】 | Synthetic peptide located within the following region: MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTK |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 85 kDa |
| species reactivity | horse, bovine, human, rat, pig |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_775490 |
| UniProt accession no.【UniProt登记号】 | P57059 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SNF1LK(150094) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
