Anti-SNX10 antibody produced in rabbit

NA.41

Sorting nexin 10 (SNX10) is a transmembrane protein belonging to SNX family. SNX10 has phox domain which binds to phosphoinositide-binding domain. In human chromosome, the gene SNX10 is located on 7p15.2.

The immunogen for anti-SNX10 antibody: synthetic peptide derected towards the middle region of human SNX10

Snx10 may be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis. Overexpression causes formation of huge vacuoles. Mutations in SNX10 leads to autosomal recessive osteoporosis due to dysregulation of osteoclasts. SNX10 interaction with vacuolar-type H⁺ -ATPase (V-ATPase) complex initiates ciliogenesis, critical for early embryonic development.

Synthetic peptide located within the following region: DFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKF

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

22 kDa

pig, horse, bovine, rat, human, mouse, rabbit

0.5 mg - 1 mg/mL

western blot: suitable

NM_001127348

Q9CWT3

wet ice

−20℃

human ... SNX10(29887)
mouse ... Snx10(71982)

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12 - Non Combustible Liquids

WGK 3